2020 · Cell Metabolism
AKG extended lifespan in ageing mice and shortened the time spent frail.
Asadi Shahmirzadi et al. · Cell Metabolism 32:447–456.e6AKG × urolithin A × ergothioneine × spermidine
Gene AKG
Multi-molecule AKG formula
Four of the most closely studied molecules in ageing research, in a single capsule: 330 mg alpha-ketoglutarate (AKG), 50 mg urolithin A, 50 mg ergothioneine and 7.5 mg spermidine — designed around cellular energy, mitochondrial health and cellular renewal.
- key molecules per capsule
- 4
- Format
- 60 capsules
- Origin
- Made in North America
| Medicinal ingredients | Per capsule |
|---|---|
| Alpha-ketoglutarate (AKG) | 330 mg |
| Ergothioneine | 50 mg |
| Urolithin A | 50 mg |
| Spermidine | 7.5 mg |
Non-medicinal ingredients: Microcrystalline cellulose, magnesium stearate
- Directions
- Use as directed on the label; do not exceed the recommended dose.
- Cautions
- Do not use if pregnant, breastfeeding or under 18. If symptoms worsen or you experience any adverse reaction, stop use and consult a physician. Keep out of reach of children; store in a cool, dark, dry place.
Science
Representative research on the ingredients in this formula — background reading, not claims about this product.
2022 · Cell Reports Medicine
4-month randomised trial: urolithin A improved muscle strength and mitochondrial-health biomarkers in middle-aged adults.
Singh et al. · Cell Reports Medicine 3:1006332016 · Nature Medicine
The natural polyamine spermidine, acting through autophagy, protected the heart and extended lifespan in mice.
Eisenberg et al. · Nature Medicine 22:1428–14382016 · Biochemical and Biophysical Research Communications
Blood ergothioneine falls with age in older adults and is lower in those with cognitive decline.
Cheah et al. · Biochemical and Biophysical Research Communications 478:162–167
Information on this website is general health information only. It is not medical advice and does not replace diagnosis or treatment by a physician. Dietary supplements are not medicines. These statements have not been evaluated by the U.S. Food and Drug Administration; products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, breastfeeding, under 18, taking medication or have a medical condition, consult a health care practitioner before use. Stem-cell, genetic-testing and blood-purification services must be delivered by appropriately licensed providers under local law; test results are for health-management reference only.
Partner with us
Every product is available for distribution and consignment, with OEM / ODM manufacturing; our health-management-centre model is open to partners across China and Southeast Asia.